Cell Adhesion Molecules and Signal Transduction.

Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins.

Trophinin in cell adhesion and signal transduction.

The process of human embryo implantation is mediated not only by evolutionarily conserved mechanisms but by activities unique to humans. Among the latter, evidence suggests that the cell adhesion molecule trophinin plays a unique role in human embryo implantation. Here, we describe characteristics of trophinin protein and of the trophinin-associated proteins bystin and tastin. We then describe ...

Cell adhesion and signal transduction in cancer

Introduction Cadherin cell-adhesion molecules and their intracellular binding partners, catenins, were discovered in the 1980s (for a review, see Takeichi, 1995). Interest in these molecules was sparked by the discovery that cadherins and, subsequently, catenins are important in the formation and metastasis of carcinomas (Behrens et al, 1989; Berx et al, 1998; Perl et al, 1998; Polakis, 2000). ...

Cell-cell adhesion and signal transduction during Dictyostelium development.

The development of the non-metazoan eukaryote Dictyostelium discoideum displays many of the features of animal embryogenesis, including regulated cell-cell adhesion. During early development, two proteins, DdCAD-1 and csA, mediate cell-cell adhesion between amoebae as they form a loosely packed multicellular mass. The mechanism governing this process is similar to epithelial sheet sealing in an...

Pathogenic interactions between Helicobacter pylori adhesion protein HopQ and human cell surface adhesion molecules CEACAMs in gastric epithelial cells

Objective(s): The present paper aims to review the studies describing the interactions between HopQ and CEACAMs along with possible mechanisms responsible for pathogenicity of Helicobacter pylori.Materials and Methods: The literature was searched on “PubMed” using different key words including Helicobacter pylori, CEACAM and gastric.<br ...